PDF DatasheetHuman Amphiregulin Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Amphiregulin based upon sequence from: Human
Host: QP10399 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Amphiregulin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10399.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is between 5-10 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR KKKNPCNAEF QNFCIHGECK YIEHLEAVTC KCQQEYFGER CGEKSMKTHS MIDSSLSK
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Amphiregulin Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Amphiregulin Protein General Information | |
|---|---|
| Alternate Names | |
| AREGB; CRDGF; AR; SDGF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | AREG |
| Entrez Gene ID | 374 |
| Ensemble Gene ID | ENSG00000109321 |
| RefSeq Protein Accession(s) | NP_001648.1 |
| RefSeq mRNA Accession(s) | NM_001657.3 |
| UniProt ID(s) | P15514 |
| HGNC ID(s) | HGNC:651 |
| COSMIC ID Link(s) | AREG |
| KEGG Gene ID(s) | hsa:374 |
| PharmGKB ID(s) | PA162376851 |
| General Description of Recombinant Human Amphiregulin Protein. | |
| Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.