PDF DatasheetHuman IFNG / Interferon Gamma Protein Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IFNG / Interferon Gamma Protein based upon sequence from: Human
Host: QP10409 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human IFNG / Interferon Gamma Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10409.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cytotoxicity assay using HT-29 cells is less than 0.05 ng/ml, corresponding to a specific activity of > 2.0 × 107 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFRGR RASQ
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human IFNG / Interferon Gamma Protein Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IFNG / Interferon Gamma Protein Protein General Information | |
|---|---|
| Alternate Names | |
| IFNG; Interferon Gamma Protein; EGK_03901; IFN-gamma | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IFNG |
| Entrez Gene ID | 3458 |
| Ensemble Gene ID | ENSG00000111537 |
| RefSeq Protein Accession(s) | NP_000610.2 |
| RefSeq mRNA Accession(s) | NM_000619.2 |
| UniProt ID(s) | P01579 |
| UniGene ID(s) | Hs.856 |
| HGNC ID(s) | HGNC:5438 |
| COSMIC ID Link(s) | IFNG |
| KEGG Gene ID(s) | hsa:3458 |
| PharmGKB ID(s) | PA29674 |
| General Description of Recombinant Human IFNG / Interferon Gamma Protein Protein. | |
| Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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