PDF DatasheetHuman LTA Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant LTA based upon sequence from Human
Host: QP1387 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human LTA, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP1387.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 5 pg/ml, corresponding to a specific activity of > 2.0 × 108 IU/mg in the presence of actinomycin D.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: LPGVGLTPSA AQTARQHPKM HLAHSTLKPA AHLIGDPSKQ NSLLWRANTD RAFLQDGFSL SNNSLLVPTS GIYFVYSQVV FSGKAYSPKA TSSPLYLAHE VQLFSSQYPF HVPLLSSQKM VYPGLQEPWL HSMYHGAAFQ LTQGDQLSTH TDGIPHLVLS PSTVFFGAFA L
Purity: Greater than 96% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human LTA Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH7.4, with 0.02 % Tween-20, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human LTA Protein General Information | |
|---|---|
| Alternate Names | |
| TNF-beta, TNFSF1, Lymphotoxin alpha Protein, TNFB, TNLG1E, LT, TNFSF1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | LTA |
| Entrez Gene ID | 4049 |
| Ensemble Gene ID | ENSG00000230279 |
| RefSeq Protein Accession(s) | NP_000586.2 |
| RefSeq mRNA Accession(s) | NM_000595.3, NM_001159740.2, XM_011514615.2, XM_011514616.2, XM_011514617.2, XM_011514618.1 |
| UniProt ID(s) | P01374 |
| UniGene ID(s) | Hs.36 |
| HGNC ID(s) | HGNC:6709 |
| COSMIC ID Link(s) | LTA |
| KEGG Gene ID(s) | hsa:4049 |
| PharmGKB ID(s) | PA30474 |
| General Description of Recombinant Human LTA Protein. | |
| Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.