PDF DatasheetHuman AKR1C2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant AKR1C2 based upon sequence from Human
Host: QP5637 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) AKR1C2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5637.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Tyr323
Amino Acid Sequence: MDSKYQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEAVKL AIEAGFHHID SAHVYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV SVKPGEEVIP KDENGKILFD TVDLCATWEA MEKCKDAGLA KSIGVSNFNH RLLEMILNKP GLKYKPVCNQ VECHPYFNQR KLLDFCKSKD IVLVAYSALG SHREEPWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTS EEMKAIDGLN RNVRYLTLDI FAGPPNYPFS DEY
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human AKR1C2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human AKR1C2 Protein General Information | |
|---|---|
| Alternate Names | |
| AKR1C2, AKR1C-pseudo, SRXY8, TDD, DD, DD-2, DDH2, DD/BABP, HAKRD, BABP, MCDR2, DD2, HBAB | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | AKR1C2 |
| Entrez Gene ID | 1646 |
| Ensemble Gene ID | ENSG00000151632 |
| RefSeq Protein Accession(s) | NP_001128713.1 |
| RefSeq mRNA Accession(s) | NM_001135241.2, NM_001354.5, NM_205845.2 |
| UniProt ID(s) | P52895 |
| UniGene ID(s) | Hs.460260 |
| HGNC ID(s) | HGNC:385 |
| COSMIC ID Link(s) | AKR1C2 |
| KEGG Gene ID(s) | hsa:1646 |
| PharmGKB ID(s) | PA24678 |
| General Description of Recombinant Human AKR1C2 Protein. | |
| Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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