PDF DatasheetHuman Aldo-keto reductase family 1 member C3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Aldo-keto reductase family 1 member C3 based upon sequence from Human
Host: QP5638 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Aldo-keto reductase family 1 member C3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5638.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD IVDLCTTWEA MEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNRS KLLDFCKSKD IVLVAYSALG SQRDKRWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTA EDMKAIDGLD RNLHYFNSDS FASHPNYPYS DEY
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Aldo-keto reductase family 1 member C3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Aldo-keto reductase family 1 member C3 Protein General Information | |
|---|---|
| Alternate Names | |
| DDX, hluPGFS, PGFS, DD3, HAKRe, HSD17B5, HA1753, HAKRB | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | AKR1C3 |
| Entrez Gene ID | 8644 |
| Ensemble Gene ID | ENSG00000196139 |
| RefSeq Protein Accession(s) | NP_001240837.1 |
| RefSeq mRNA Accession(s) | NM_001253908.1, NM_003739.5 |
| UniProt ID(s) | P42330 |
| UniGene ID(s) | Hs.78183 |
| HGNC ID(s) | HGNC:386 |
| COSMIC ID Link(s) | AKR1C3 |
| KEGG Gene ID(s) | hsa:8644 |
| PharmGKB ID(s) | PA24679 |
| General Description of Recombinant Human Aldo-keto reductase family 1 member C3 Protein. | |
| Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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