PDF DatasheetHuman Annexin A2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Annexin A2 based upon sequence from Human
Host: QP5652 protein expressed in E.coli, Mammal..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Annexin A2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5652.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ser2 – Asp339
Amino Acid Sequence: STVHEILCKL SLEGDHSTPP SAYGSVKAYT NFDAERDALN IETAIKTKGV DEVTIVNILT NRSNAQRQDI AFAYQRRTKK ELASALKSAL SGHLETVILG LLKTPAQYDA SELKASMKGL GTDEDSLIEI ICSRTNQELQ EINRVYKEMY KTDLEKDIIS DTSGDFRKLM VALAKGRRAE DGSVIDYELI DQDARDLYDA GVKRKGTDVP KWISIMTERS VPHLQKVFDR YKSYSPYDML ESIRKEVKGD LENAFLNLVQ CIQNKPLYFA DRLYDSMKGK GTRDKVLIRI MVSRSEVDML KIRSEFKRKY GKSLYYYIQQ DTKGDYQKAL LYLCGGDD
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Annexin A2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Annexin A2 Protein General Information | |
|---|---|
| Alternate Names | |
| LPC2, ANX2L4, LIP2, LPC2D, PAP-IV, ANX2, P36, HEL-S-270, CAL1H | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ANXA2 |
| Entrez Gene ID | 302 |
| Ensemble Gene ID | ENSG00000182718 |
| RefSeq Protein Accession(s) | NP_001002857.1 |
| RefSeq mRNA Accession(s) | NM_001002857.1, NM_001002858.2, NM_001136015.2, NM_004039.2, XM_017022090.1, XM_017022091.1 |
| UniProt ID(s) | P07355 |
| UniGene ID(s) | Hs.511605 |
| HGNC ID(s) | HGNC:537 |
| COSMIC ID Link(s) | ANXA2 |
| KEGG Gene ID(s) | hsa:302 |
| PharmGKB ID(s) | PA24827 |
| General Description of Recombinant Human Annexin A2 Protein. | |
| Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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