Mouse Apolipoprotein C-III Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Apolipoprotein C-III based upon sequence from Mouse
Host: QP5667 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Apolipoprotein C-III, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5667.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu21 – Ser99
Amino Acid Sequence: EEVEGSLLLG SVQGYMEQAS KTVQDALSSV QESDIAVVAR GWMDNHFRFL KGYWSKFTDK FTGFWDSNPE DQPTPAIES
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Apolipoprotein C-III Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Mouse Apolipoprotein C-III Protein General Information | |
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Alternate Names | |
apo-CIII, apoC-III | |
Curated Database and Bioinformatic Data | |
Gene Symbol | APOC3 |
Entrez Gene ID | 11814 |
RefSeq Protein Accession(s) | NP_001276685.1 |
RefSeq mRNA Accession(s) | NM_001289756.1, NM_023114.4 |
UniProt ID(s) | P33622 |
UniGene ID(s) | Mm.390161 |
COSMIC ID Link(s) | APOC3 |
KEGG Gene ID(s) | mmu:11814 |
General Description of Recombinant Mouse Apolipoprotein C-III Protein. | |
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assbly and secretion; Extracellular domainly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by rnant receptors. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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