PDF DatasheetHuman ADP-ribosylation factor 6 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant ADP-ribosylation factor 6 based upon sequence from Human
Host: QP5674 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) ADP-ribosylation factor 6, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5674.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ser175
Amino Acid Sequence: MGKVLSKIFG NKEMRILMLG LDAAGKTTIL YKLKLGQSVT TIPTVGFNVE TVTYKNVKFN VWDVGGQDKI RPLWRHYYTG TQGLIFVVDC ADRDRIDEAR QELHRIINDR EMRDAIILIF ANKQDLPDAM KPHEIQEKLG LTRIRDRNWY VQPSCATSGD GLYEGLTWLT SNYKS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human ADP-ribosylation factor 6 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human ADP-ribosylation factor 6 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ARF6 |
| Entrez Gene ID | 382 |
| Ensemble Gene ID | ENSG00000165527 |
| RefSeq Protein Accession(s) | NP_001654.1 |
| RefSeq mRNA Accession(s) | NM_001663.3 |
| UniProt ID(s) | P62330 |
| UniGene ID(s) | Hs.525330 |
| HGNC ID(s) | HGNC:659 |
| COSMIC ID Link(s) | ARF6 |
| KEGG Gene ID(s) | hsa:382 |
| PharmGKB ID(s) | PA24942 |
| General Description of Recombinant Human ADP-ribosylation factor 6 Protein. | |
| GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton rodeling. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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