PDF DatasheetHuman ASCC3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant ASCC3 based upon sequence from Human
Isoform: Isoform 2
Host: QP5683 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) ASCC3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5683.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 2
Expression Region: Met1 – Arg111
Amino Acid Sequence: MALPRLTGAL RSFSNVTKQD NYNEEVADLK IKRSKLHEQV LDLGLTWKKI IKFLNEKLEK SKMQSINEDL KDILHAAKQI EVNCPFQKRR LDGKEEDEKM SRASDRFRGL R
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human ASCC3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human ASCC3 Protein General Information | |
|---|---|
| Alternate Names | |
| HELIC1, ASC1p200, RNAH, Activating signal cointegrator 1 complex subunit | |
| Molecular Weight | |
| Isoform 2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ASCC3 |
| Entrez Gene ID | 10973 |
| Ensemble Gene ID | ENSG00000112249 |
| RefSeq Protein Accession(s) | NP_001271200.1 |
| RefSeq mRNA Accession(s) | NM_001284271.1, NM_006828.3, NM_022091.4 |
| UniProt ID(s) | Q8N3C0 |
| UniGene ID(s) | Hs.486031 |
| HGNC ID(s) | HGNC:18697 |
| COSMIC ID Link(s) | ASCC3 |
| KEGG Gene ID(s) | hsa:10973 |
| PharmGKB ID(s) | PA134890913 |
| General Description of Recombinant Human ASCC3 Protein. | |
| 3′-5′ DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Enhances NF-kappa-B, SRF and AP1 transactivation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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