Mouse ASGPR1 / ASGR1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant ASGPR1 / ASGR1 based upon sequence from Mouse
Host: QP5684 protein expressed in E.coli, Yeast..
Tag: GST
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) ASGPR1 / ASGR1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5684.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Gln61 – Asn284
Amino Acid Sequence: QNSQLREDLL ALRQNFSNLT VSTEDQVKAL STQGSSVGRK MKLVESKLEK QQKDLTEDHS SLLLHVKQLV SDVRSLSCQM AAFRGNGSER TCCPINWVEY EGSCYWFSSS VRPWTEADKY CQLENAHLVV VTSRDEQNFL QRHMGPLNTW IGLTDQNGPW KWVDGTDYET GFQNWRPEQP DNWYGHGLGG GEDCAHFTTD GRWNDDVCRR PYRWVCETKL DKAN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse ASGPR1 / ASGR1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Mouse ASGPR1 / ASGR1 Protein General Information | |
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Curated Database and Bioinformatic Data | |
Gene Symbol | Asgr1 |
Entrez Gene ID | 11889 |
Ensemble Gene ID | ENSMUSG00000020884 |
RefSeq Protein Accession(s) | NP_001278060.1 |
RefSeq mRNA Accession(s) | NM_001291131.1, NM_001291132.1, NM_009714.3, XM_017314231.1 |
UniProt ID(s) | P34927 |
UniGene ID(s) | Mm.6559 |
COSMIC ID Link(s) | Asgr1 |
KEGG Gene ID(s) | mmu:11889 |
General Description of Recombinant Mouse ASGPR1 / ASGR1 Protein. | |
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been roved. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell mbrane surface. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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