PDF DatasheetHuman Bcl-2-like protein 11 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Bcl-2-like protein 11 based upon sequence from Human
Host: QP5712 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Bcl-2-like protein 11, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5712.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – His198
Amino Acid Sequence: MAKQPSDVSS ECDREGRQLQ PAERPPQLRP GAPTSLQTEP QGNPEGNHGG EGDSCPHGSP QGPLAPPASP GPFATRSPLF IFMRRSSLLS RSSSGYFSFD TDRSPAPMSC DKSTQTPSPP CQAFNHYLSA MASMRQAEPA DMRPEIWIAQ ELRRIGDEFN AYYARRVFLN NYQAAEDHPR MVILRLLRYI VRLVWRMH
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Bcl-2-like protein 11 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Bcl-2-like protein 11 Protein General Information | |
|---|---|
| Alternate Names | |
| BOD, BAM, BIM | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | BCL2L11 |
| Entrez Gene ID | 10018 |
| Ensemble Gene ID | ENSG00000153094 |
| RefSeq Protein Accession(s) | NP_001191035.1 |
| RefSeq mRNA Accession(s) | NM_001204106.1, NM_001204107.1, NM_001204108.1, NM_001204109.1, NM_001204110.1, NM_001204111.1, NM_001204112.1, NM_001204113.1, NM_006538.4, NM_138621.4, NM_138622.3, NM_138623.3, NM_138624.3, NM_138625.3, NM_138626.3, NM_138627.3, NM_207002.3, NM_207003.2 |
| UniProt ID(s) | O43521 |
| UniGene ID(s) | Hs.469658 |
| HGNC ID(s) | HGNC:994 |
| COSMIC ID Link(s) | BCL2L11 |
| KEGG Gene ID(s) | hsa:10018 |
| PharmGKB ID(s) | PA25305 |
| General Description of Recombinant Human Bcl-2-like protein 11 Protein. | |
| Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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