PDF DatasheetHuman ALK-3 / BMPR1A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant ALK-3 / BMPR1A based upon sequence from Human
Host: QP5725 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) ALK-3 / BMPR1A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5725.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Lys177 – Ile532
Amino Acid Sequence: KHYCKSISSR RRYNRDLEQD EAFIPVGESL KDLIDQSQSS GSGSGLPLLV QRTIAKQIQM VRQVGKGRYG EVWMGKWRGE KVAVKVFFTT EEASWFRETE IYQTVLMRHE NILGFIAADI KGTGSWTQLY LITDYHENGS LYDFLKCATL DTRALLKLAY SAACGLCHLH TEIYGTQGKP AIAHRDLKSK NILIKKNGSC CIADLGLAVK FNSDTNEVDV PLNTRVGTKR YMAPEVLDES LNKNHFQPYI MADIYSFGLI IWEMARRCIT GGIVEEYQLP YYNMVPSDPS YEDMREVVCV KRLRPIVSNR WNSDECLRAV LKLMSECWAH NPASRLTALR IKKTLAKMVE SQDVKI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human ALK-3 / BMPR1A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human ALK-3 / BMPR1A Protein General Information | |
|---|---|
| Alternate Names | |
| ALK-3, BMPR1A, 1110037I22Rik, AU045487, BMPR-IA, ALK3, Bmpr | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | BMPR1A |
| Entrez Gene ID | 657 |
| Ensemble Gene ID | ENSG00000107779 |
| RefSeq Protein Accession(s) | NP_004320.2 |
| RefSeq mRNA Accession(s) | NM_004329.2, XM_011540103.2, XM_011540104.2 |
| UniProt ID(s) | P36894 |
| UniGene ID(s) | Hs.524477 |
| HGNC ID(s) | HGNC:1076 |
| COSMIC ID Link(s) | BMPR1A |
| KEGG Gene ID(s) | hsa:657 |
| PharmGKB ID(s) | PA25386 |
| General Description of Recombinant Human ALK-3 / BMPR1A Protein. | |
| On ligand binding, forms a receptor complex consisting of two type II and two type I transmbrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4. Positively regulates chondrocyte differentiation through GDF5 interaction . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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