PDF DatasheetHuman Anaphase-promoting complex subunit 15 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Anaphase-promoting complex subunit 15 based upon sequence from Human
Host: QP5732 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Anaphase-promoting complex subunit 15, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5732.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ile121
Amino Acid Sequence: MSTLFPSLFP RVTETLWFNL DRPCVEETEL QQQEQQHQAW LQSIAEKDNN LVPIGKPASE HYDDEEEEDD EDDEDSEEDS EDDEDMQDMD EMNDYNESPD DGEVNEVDME GNEQDQDQWM I
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Anaphase-promoting complex subunit 15 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Anaphase-promoting complex subunit 15 Protein General Information | |
|---|---|
| Alternate Names | |
| C11orf51, HSPC020, APC15 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ANAPC15 |
| Entrez Gene ID | 25906 |
| Ensemble Gene ID | ENSG00000110200 |
| RefSeq Protein Accession(s) | NP_001265414.1 |
| RefSeq mRNA Accession(s) | NM_001278485.1, NM_001278486.1, NM_001278487.1, NM_001278488.1, NM_001278489.1, NM_001278490.1, NM_001278491.1, NM_001278492.1, NM_001278493.1, NM_001278494.1, NM_014042.2, XM_017017496.1, XM_017017497.1 |
| UniProt ID(s) | P60006 |
| UniGene ID(s) | Hs.38044 |
| HGNC ID(s) | HGNC:24531 |
| KEGG Gene ID(s) | hsa:25906 |
| PharmGKB ID(s) | PA143485346 |
| General Description of Recombinant Human Anaphase-promoting complex subunit 15 Protein. | |
| Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assbly checkpoint. Also required for degradation of CDC20. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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