PDF DatasheetHuman F-actin-capping protein subunit alpha-2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant F-actin-capping protein subunit alpha-2 based upon sequence from Human
Host: QP5759 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) F-actin-capping protein subunit alpha-2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5759.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Ala286
Amino Acid Sequence: ADLEEQLSDE EKVRIAAKFI IHAPPGEFNE VFNDVRLLLN NDNLLREGAA HAFAQYNLDQ FTPVKIEGYE DQVLITEHGD LGNGKFLDPK NRICFKFDHL RKEATDPRPC EVENAVESWR TSVETALRAY VKEHYPNGVC TVYGKKIDGQ QTIIACIESH QFQAKNFWNG RWRSEWKFTI TPSTTQVVGI LKIQVHYYED GNVQLVSHKD IQDSLTVSNE VQTAKEFIKI VEAAENEYQT AISENYQTMS DTTFKALRRQ LPVTRTKIDW NKILSYKIGK EMQNA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human F-actin-capping protein subunit alpha-2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human F-actin-capping protein subunit alpha-2 Protein General Information | |
|---|---|
| Alternate Names | |
| CAPPA2, CAPZ | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CAPZA2 |
| Entrez Gene ID | 830 |
| Ensemble Gene ID | ENSG00000198898 |
| RefSeq Protein Accession(s) | NP_006127.1 |
| RefSeq mRNA Accession(s) | NM_006136.2 |
| UniProt ID(s) | P47755 |
| UniGene ID(s) | Hs.446123 |
| HGNC ID(s) | HGNC:1490 |
| COSMIC ID Link(s) | CAPZA2 |
| KEGG Gene ID(s) | hsa:830 |
| PharmGKB ID(s) | PA26071 |
| General Description of Recombinant Human F-actin-capping protein subunit alpha-2 Protein. | |
| F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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