PDF DatasheetHuman F-actin-capping protein subunit beta Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant F-actin-capping protein subunit beta based upon sequence from Human
Isoform: Isoform 2
Host: QP5760 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) F-actin-capping protein subunit beta, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5760.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 2
Expression Region: Met1 – Cys272
Amino Acid Sequence: MSDQQLDCAL DLMRRLPPQQ IEKNLSDLID LVPSLCEDLL SSVDQPLKIA RDKVVGKDYL LCDYNRDGDS YRSPWSNKYD PPLEDGAMPS ARLRKLEVEA NNAFDQYRDL YFEGGVSSVY LWDLDHGFAG VILIKKAGDG SKKIKGCWDS IHVVEVQEKS SGRTAHYKLT STVMLWLQTN KSGSGTMNLG GSLTRQMEKD ETVSDCSPHI ANIGRLVEDM ENKIRSTLNE IYFGKTKDIV NGLRSVQTFA DKSKQEALKN DLVEALKRKQ QC
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human F-actin-capping protein subunit beta Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human F-actin-capping protein subunit beta Protein General Information | |
|---|---|
| Alternate Names | |
| CAPB, CAPZ, CAPPB | |
| Molecular Weight | |
| Isoform 2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CAPZB |
| Entrez Gene ID | 832 |
| Ensemble Gene ID | ENSG00000077549 |
| RefSeq Protein Accession(s) | NP_001193469.1 |
| RefSeq mRNA Accession(s) | NM_001206540.2, NM_001282162.1, NM_004930.4 |
| UniProt ID(s) | P47756 |
| UniGene ID(s) | Hs.432760 |
| HGNC ID(s) | HGNC:1491 |
| COSMIC ID Link(s) | CAPZB |
| KEGG Gene ID(s) | hsa:832 |
| PharmGKB ID(s) | PA26072 |
| General Description of Recombinant Human F-actin-capping protein subunit beta Protein. | |
| F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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