PDF DatasheetMouse CD63 / Tspan-30 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CD63 / Tspan-30 based upon sequence from Mouse
Host: QP5792 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) CD63 / Tspan-30, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5792.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Ala103 – Ile203
Amino Acid Sequence: AGYVFRDQVK SEFNKSFQQQ MQNYLKDNKT ATILDKLQKE NNCCGASNYT DWENIPGMAK DRVPDSCCIN ITVGCGNDFK ESTIHTQGCV ETIAIWLRKN I
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse CD63 / Tspan-30 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse CD63 / Tspan-30 Protein General Information | |
|---|---|
| Alternate Names | |
| CD63, Tspan-30, ME491, TSPAN30, MLA1, OMA81H, LAMP-3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Cd63 |
| Entrez Gene ID | 12512 |
| Ensemble Gene ID | ENSMUSG00000025351 |
| RefSeq Protein Accession(s) | NP_001036045.1 |
| RefSeq mRNA Accession(s) | NM_001042580.1, NM_001282966.1, NM_007653.3 |
| UniProt ID(s) | P41731 |
| UniGene ID(s) | Mm.371552 |
| COSMIC ID Link(s) | Cd63 |
| KEGG Gene ID(s) | mmu:12512 |
| General Description of Recombinant Mouse CD63 / Tspan-30 Protein. | |
| Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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