PDF DatasheetHuman Centromere protein H Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Centromere protein H based upon sequence from Human
Host: QP5818 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Centromere protein H, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5818.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Met247
Amino Acid Sequence: MEEQPQMQDA DEPADSGGEG RAGGPPQVAG AQAACSEDRM TLLLRLRAQT KQQLLEYKSM VDASEEKTPE QIMQEKQIEA KIEDLENEIE EVKVAFEIKK LALDRMRLST ALKKNLEKIS RQSSVLMDNM KHLLELNKLI MKSQQESWDL EEKLLDIRKK RLQLKQASES KLLEIQTEKN KQKIDLDSME NSERIKIIRQ NLQMEIKITT VIQHVFQNLI LGSKVNWAED PALKEIVLQL EKNVDMM
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Centromere protein H Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Centromere protein H Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CENPH |
| Entrez Gene ID | 64946 |
| Ensemble Gene ID | ENSG00000153044 |
| RefSeq Protein Accession(s) | NP_075060.1 |
| RefSeq mRNA Accession(s) | NM_022909.3 |
| UniProt ID(s) | Q9H3R5 |
| UniGene ID(s) | Hs.631967 |
| HGNC ID(s) | HGNC:17268 |
| COSMIC ID Link(s) | CENPH |
| KEGG Gene ID(s) | hsa:64946 |
| PharmGKB ID(s) | PA26402 |
| General Description of Recombinant Human Centromere protein H Protein. | |
| Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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