PDF DatasheetHuman Centromere protein K Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Centromere protein K based upon sequence from Human
Host: QP5819 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Centromere protein K, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5819.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Gln269
Amino Acid Sequence: MNQEDLDPDS TTDVGDVTNT EEELIRECEE MWKDMEECQN KLSLIGTETL TDSNAQLSLL IMQVKCLTAE LSQWQKKTPE TIPLTEDVLI TLGKEEFQKL RQDLEMVLST KESKNEKLKE DLEREQRWLD EQQQIMESLN VLHSELKNKV ETFSESRIFN ELKTKMLNIK EYKEKLLSTL GEFLEDHFPL PDRSVKKKKK NIQESSVNLI TLHEMLEILI NRLFDVPHDP YVKISDSFWP PYVELLLRNG IALRHPEDPT RIRLEAFHQ
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Centromere protein K Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Centromere protein K Protein General Information | |
|---|---|
| Alternate Names | |
| CENP-K, FKSG14, P33, Solt, AF5alpha | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CENPK |
| Entrez Gene ID | 64105 |
| Ensemble Gene ID | ENSG00000123219 |
| RefSeq Protein Accession(s) | NP_001253967.1 |
| RefSeq mRNA Accession(s) | NM_001267038.1, NM_022145.4, XM_011543536.2, XM_017009690.1, XM_017009691.1, XM_017009692.1 |
| UniProt ID(s) | Q9BS16 |
| UniGene ID(s) | Hs.529778 |
| HGNC ID(s) | HGNC:29479 |
| COSMIC ID Link(s) | CENPK |
| KEGG Gene ID(s) | hsa:64105 |
| PharmGKB ID(s) | PA145149171 |
| General Description of Recombinant Human Centromere protein K Protein. | |
| Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with CASC5/KNL1 to recruit the NDC80 complex to the outer kinetochore. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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