PDF DatasheetMouse complement factor B Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant complement factor B based upon sequence from Mouse
Host: QP5822 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) complement factor B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5822.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Val23 – Leu761
Amino Acid Sequence: VTTTPWSLAR PQGSCSLEGV EIKGGSFRLL QEGQALEYVC PSGFYPYPVQ TRTCRSTGSW STLKTQDQKT VRKAECRAIH CPRPHDFENG EYWPRSPYYN VSDEISFHCY DGYTLRGSAN RTCQVNGRWS GQTAICDNGA GYCSNPGIPI GTRKVGSQYR LEDSVTYHCS RGLTLRGSQR RTCQEGGSWS GTEPSCQDSF MYDTPQEVAE AFLSSLTETI EGVDAEDGHG PGEQQKRKIV LDPSGSMNIY LVLDGSDSIG ASNFTGAKKC LVNLIEKVAS YGVKPRYGLV TYATYPKIWV KVSEADSSNA DWVTKQLNEI NYEDHKLKSG TNTKKALQAV YSMMSWPDDV PPEGWNRTRH VIILMTDGLH NMGGDPITVI DEIRDLLYIG KDRKNPREDY LDVYVFGVGP LVNQVNINAL ASKKDNEQHV FKVKDMENLE DVFYQMIDES QSLSLCGMVW EHRKGTDYHK QPWQAKISVI RPSKGHESCM GAVVSEYFVL TAAHCFTVDD KEHSIKVSVG GEKRDLEIEV VLFHPNYNIN GKKEAGIPEF YDYDVALIKL KNKLKYGQTI RPICLPCTEG TTRALRLPPT TTCQQQKEEL LPAQDIKALF VSEEEKKLTR KEVYIKNGDK KGSCERDAQY APGYDKVKDI SEVVTPRFLC TGGVSPYADP NTCRGDSGGP LIVHKRSRFI QVGVISWGVV DVCKNQKRQK QVPAHARDFH INLFQVLPWL KEKLQDEDL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse complement factor B Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse complement factor B Protein General Information | |
|---|---|
| Alternate Names | |
| complement factor B, AHUS4, FB, FBI12, ARMD14, BF, CFAB, H2-Bf, BFD, CFBD, GBG, PBF2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CFB |
| Entrez Gene ID | 629 |
| Ensemble Gene ID | ENSG00000241253 |
| RefSeq Protein Accession(s) | NP_001701.2 |
| RefSeq mRNA Accession(s) | NM_001710.5 |
| UniProt ID(s) | P00751 |
| UniGene ID(s) | Hs.69771 |
| HGNC ID(s) | HGNC:1037 |
| COSMIC ID Link(s) | CFB |
| KEGG Gene ID(s) | hsa:629 |
| PharmGKB ID(s) | PA25341 |
| General Description of Recombinant Mouse complement factor B Protein. | |
| Factor B which is part of the alternate pathway of the complent syst is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complent factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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