PDF DatasheetHuman CFL2 / cofilin 2 / ADF Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CFL2 / cofilin 2 / ADF based upon sequence from Human
Host: QP5825 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CFL2 / cofilin 2 / ADF, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5825.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Leu166
Amino Acid Sequence: MASGVTVNDE VIKVFNDMKV RKSSTQEEIK KRKKAVLFCL SDDKRQIIVE EAKQILVGDI GDTVEDPYTS FVKLLPLNDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKLGGNVVVS LEGKPL
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human CFL2 / cofilin 2 / ADF Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CFL2 / cofilin 2 / ADF Protein General Information | |
|---|---|
| Alternate Names | |
| CFL2, cofilin 2, ADF, NEM7 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CFL2 |
| Entrez Gene ID | 1073 |
| Ensemble Gene ID | ENSG00000165410 |
| RefSeq Protein Accession(s) | NP_001230574.1 |
| RefSeq mRNA Accession(s) | NM_001243645.1, NM_021914.7, NM_138638.4, XM_011536363.2 |
| UniProt ID(s) | Q9Y281 |
| UniGene ID(s) | Hs.180141 |
| HGNC ID(s) | HGNC:1875 |
| COSMIC ID Link(s) | CFL2 |
| KEGG Gene ID(s) | hsa:1073 |
| PharmGKB ID(s) | PA26424 |
| General Description of Recombinant Human CFL2 / cofilin 2 / ADF Protein. | |
| Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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