PDF DatasheetHuman Chromogranin A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Chromogranin A based upon sequence from Human
Host: QP5827 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Chromogranin A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5827.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Leu19 – Gly457
Amino Acid Sequence: LPVNSPMNKG DTEVMKCIVE VISDTLSKPS PMPVSQECFE TLRGDERILS ILRHQNLLKE LQDLALQGAK ERAHQQKKHS GFEDELSEVL ENQSSQAELK EAVEEPSSKD VMEKREDSKE AEKSGEATDG ARPQALPEPM QESKAEGNNQ APGEEEEEEE EATNTHPPAS LPSQKYPGPQ AEGDSEGLSQ GLVDREKGLS AEPGWQAKRE EEEEEEEEAE AGEEAVPEEE GPTVVLNPHP SLGYKEIRKG ESRSEALAVD GAGKPGAEEA QDPEGKGEQE HSQQKEEEEE MAVVPQGLFR GGKSGELEQE EERLSKEWED SKRWSKMDQL AKELTAEKRL EGQEEEEDNR DSSMKLSFRA RAYGFRGPGP QLRRGWRPSS REDSLEAGLP LQVRGYPEEK KEEEGSANRR PEDQELESLS AIEAELEKVA HQLQALRRG
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Chromogranin A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Chromogranin A Protein General Information | |
|---|---|
| Alternate Names | |
| Chromogranin A, CGA | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CHGA |
| Entrez Gene ID | 1113 |
| Ensemble Gene ID | ENSG00000100604 |
| RefSeq Protein Accession(s) | NP_001266.1 |
| RefSeq mRNA Accession(s) | NM_001275.3, NM_001301690.1, XM_011536370.1 |
| UniProt ID(s) | P10645 |
| UniGene ID(s) | Hs.150793 |
| HGNC ID(s) | HGNC:1929 |
| COSMIC ID Link(s) | CHGA |
| KEGG Gene ID(s) | hsa:1113 |
| PharmGKB ID(s) | PA26461 |
| General Description of Recombinant Human Chromogranin A Protein. | |
| Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas.Catestatin: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist . Displays antibacterial activity against Gram-positive bacteria S.aureus and M.luteus, and Gram-negative bacteria E.coli and P.aeruginosa . Can induce mast cell migration, degranulation and production of cytokines and chokines . Acts as a potent scavenger of free radicals in vitro . May play a role in the regulation of cardiac function and blood pressure . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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