PDF DatasheetHuman Chromogranin A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Chromogranin A based upon sequence from Human
Host: QP5828 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Chromogranin A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5828.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Gln224 – Gly457
Amino Acid Sequence: QAKREEEEEE EEEAEAGEEA VPEEEGPTVV LNPHPSLGYK EIRKGESRSE ALAVDGAGKP GAEEAQDPEG KGEQEHSQQK EEEEEMAVVP QGLFRGGKSG ELEQEEERLS KEWEDSKRWS KMDQLAKELT AEKRLEGQEE EEDNRDSSMK LSFRARAYGF RGPGPQLRRG WRPSSREDSL EAGLPLQVRG YPEEKKEEEG SANRRPEDQE LESLSAIEAE LEKVAHQLQA LRRG
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Chromogranin A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Chromogranin A Protein General Information | |
|---|---|
| Alternate Names | |
| Chromogranin A, CGA | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CHGA |
| Entrez Gene ID | 1113 |
| Ensemble Gene ID | ENSG00000100604 |
| RefSeq Protein Accession(s) | NP_001266.1 |
| RefSeq mRNA Accession(s) | NM_001275.3, NM_001301690.1, XM_011536370.1 |
| UniProt ID(s) | P10645 |
| UniGene ID(s) | Hs.150793 |
| HGNC ID(s) | HGNC:1929 |
| COSMIC ID Link(s) | CHGA |
| KEGG Gene ID(s) | hsa:1113 |
| PharmGKB ID(s) | PA26461 |
| General Description of Recombinant Human Chromogranin A Protein. | |
| Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas.Catestatin: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist . Displays antibacterial activity against Gram-positive bacteria S.aureus and M.luteus, and Gram-negative bacteria E.coli and P.aeruginosa . Can induce mast cell migration, degranulation and production of cytokines and chokines . Acts as a potent scavenger of free radicals in vitro . May play a role in the regulation of cardiac function and blood pressure . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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