PDF DatasheetHuman Acetylcholine receptor subunit alpha Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Acetylcholine receptor subunit alpha based upon sequence from Human
Host: QP5832 protein expressed in E. coli.
Tag: His-Trx
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Acetylcholine receptor subunit alpha, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5832.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Ser21 – Leu255
Amino Acid Sequence: SEHETRLVAK LFKDYSSVVR PVEDHRQVVE VTVGLQLIQL INVDEVNQIV TTNVRLKQGD MVDLPRPSCV TLGVPLFSHL QNEQWVDYNL KWNPDDYGGV KKIHIPSEKI WRPDLVLYNN ADGDFAIVKF TKVLLQYTGH ITWTPPAIFK SYCEIIVTHF PFDEQNCSMK LGTWTYDGSV VAINPESDQP DLSNFMESGE WVIKESRGWK HSVTYSCCPD TPYLDITYHF VMQRL
Purity: Greater than 82.8% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Acetylcholine receptor subunit alpha Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Acetylcholine receptor subunit alpha Protein General Information | |
|---|---|
| Alternate Names | |
| CMS1A, CMS1B, CMS2A, ACHRA, FCCMS, CHRNA, SCCMS, ACHRD | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CHRNA1 |
| Entrez Gene ID | 1134 |
| Ensemble Gene ID | ENSG00000138435 |
| RefSeq Protein Accession(s) | NP_000070.1 |
| RefSeq mRNA Accession(s) | NM_000079.3, NM_001039523.2 |
| UniProt ID(s) | P02708 |
| UniGene ID(s) | Hs.434479 |
| HGNC ID(s) | HGNC:1955 |
| COSMIC ID Link(s) | CHRNA1 |
| KEGG Gene ID(s) | hsa:1134 |
| PharmGKB ID(s) | PA26487 |
| General Description of Recombinant Human Acetylcholine receptor subunit alpha Protein. | |
| After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma mbrane. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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