PDF DatasheetHuman CHRNA3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CHRNA3 based upon sequence from Human
Host: QP5835 protein expressed in E. coli.
Tag: HIs-Myc
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CHRNA3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5835.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Ser32 – Leu240
Amino Acid Sequence: SEAEHRLFER LFEDYNEIIR PVANVSDPVI IHFEVSMSQL VKVDEVNQIM ETNLWLKQIW NDYKLKWNPS DYGGAEFMRV PAQKIWKPDI VLYNNAVGDF QVDDKTKALL KYTGEVTWIP PAIFKSSCKI DVTYFPFDYQ NCTMKFGSWS YDKAKIDLVL IGSSMNLKDY WESGEWAIIK APGYKHDIKY NCCEEIYPDI TYSLYIRRL
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human CHRNA3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CHRNA3 Protein General Information | |
|---|---|
| Alternate Names | |
| LNCR2, PAOD2, NACHRA3, Neuronal acetylcholine receptor subunit alpha | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CHRNA3 |
| Entrez Gene ID | 1136 |
| Ensemble Gene ID | ENSG00000080644 |
| RefSeq Protein Accession(s) | NP_000734.2 |
| RefSeq mRNA Accession(s) | NM_000743.4, NM_001166694.1 |
| UniProt ID(s) | P32297 |
| UniGene ID(s) | Hs.89605 |
| HGNC ID(s) | HGNC:1957 |
| COSMIC ID Link(s) | CHRNA3 |
| KEGG Gene ID(s) | hsa:1136 |
| PharmGKB ID(s) | PA113 |
| General Description of Recombinant Human CHRNA3 Protein. | |
| After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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