PDF DatasheetHuman COL4A3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant COL4A3 based upon sequence from Human
Host: QP5853 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) COL4A3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5853.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Phe1446 – Lys1667
Amino Acid Sequence: FVFTRHSQTT AIPSCPEGTV PLYSGFSFLF VQGNQRAHGQ DLGTLGSCLQ RFTTMPFLFC NVNDVCNFAS RNDYSYWLST PALMPMNMAP ITGRALEPYI SRCTVCEGPA IAIAVHSQTT DIPPCPHGWI SLWKGFSFIM FTSAGSEGTG QALASPGSCL EEFRASPFLE CHGRGTCNYY SNSYSFWLAS LNPERMFRKP IPSTVKAGEL EKIISRCQVC MK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human COL4A3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human COL4A3 Protein General Information | |
|---|---|
| Alternate Names | |
| COL4A3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | COL4A3 |
| Entrez Gene ID | 1285 |
| Ensemble Gene ID | ENSG00000169031 |
| RefSeq Protein Accession(s) | NP_000082.2 |
| RefSeq mRNA Accession(s) | NM_000091.4 |
| UniProt ID(s) | Q01955 |
| UniGene ID(s) | Hs.570065 |
| HGNC ID(s) | HGNC:2204 |
| COSMIC ID Link(s) | COL4A3 |
| KEGG Gene ID(s) | hsa:1285 |
| PharmGKB ID(s) | PA26719 |
| General Description of Recombinant Human COL4A3 Protein. | |
| Type IV collagen is the major structural component of glomerular basent mbranes (GBM), forming a ‘chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen.Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity; these two anti-tumor properties may be regulated via RGD-independent ITGB3-mediated mechanisms. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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