PDF DatasheetHuman CPSF4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CPSF4 based upon sequence from Human
Isoform: Isoform 2
Host: QP5858 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CPSF4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5858.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 2
Expression Region: Met1 – Gln244
Amino Acid Sequence: MQEIIASVDH IKFDLEIAVE QQLGAQPLPF PGMDKSGAAV CEFFLKAACG KGGMCPFRHI SGEKTVVCKH WLRGLCKKGD QCEFLHEYDM TKMPECYFYS KFGECSNKEC PFLHIDPESK IKDCPWYDRG FCKHGPLCRH RHTRRVICVN YLVGFCPEGP SCKFMHPRFE LPMGTTEQPP LPQQTQPPAK QRTPQVIGVM QSQNSSAGNR GPRPLEQVTC YKCGEKGHYA NRCTKGHLAF LSGQ
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human CPSF4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CPSF4 Protein General Information | |
|---|---|
| Alternate Names | |
| NEB-1, CPSF30, NAR, NEB1, Cleavage and polyadenylation specificity factor subunit | |
| Molecular Weight | |
| Isoform 2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CPSF4 |
| Entrez Gene ID | 10898 |
| Ensemble Gene ID | ENSG00000160917 |
| RefSeq Protein Accession(s) | NP_001075028.1 |
| RefSeq mRNA Accession(s) | NM_001081559.2, NM_001318160.1, NM_001318161.1, NM_001318162.1, NM_006693.3 |
| UniProt ID(s) | O95639 |
| UniGene ID(s) | Hs.489287 |
| HGNC ID(s) | HGNC:2327 |
| COSMIC ID Link(s) | CPSF4 |
| KEGG Gene ID(s) | hsa:10898 |
| PharmGKB ID(s) | PA26844 |
| General Description of Recombinant Human CPSF4 Protein. | |
| Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3′-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.