PDF DatasheetHuman CREB1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CREB1 based upon sequence from Human
Host: QP5866 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CREB1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5866.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Asp341
Amino Acid Sequence: MTMESGAENQ QSGDAAVTEA ENQQMTVQAQ PQIATLAQVS MPAAHATSSA PTVTLVQLPN GQTVQVHGVI QAAQPSVIQS PQVQTVQSSC KDLKRLFSGT QISTIAESED SQESVDSVTD SQKRREILSR RPSYRKILND LSSDAPGVPR IEEEKSEEET SAPAITTVTV PTPIYQTSSG QYIAITQGGA IQLANNGTDG VQGLQTLTMT NAAATQPGTT ILQYAQTTDG QQILVPSNQV VVQAASGDVQ TYQIRTAPTS TIAPGVVMAS SPALPTQPAE EAARKREVRL MKNREAAREC RRKKKEYVKC LENRVAVLEN QNKTLIEELK ALKDLYCHKS D
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human CREB1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CREB1 Protein General Information | |
|---|---|
| Alternate Names | |
| CREB-1, CREB, Cyclic AMP-responsive element-binding protein | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CREB1 |
| Entrez Gene ID | 1385 |
| Ensemble Gene ID | ENSG00000118260 |
| RefSeq Protein Accession(s) | NP_004370.1 |
| RefSeq mRNA Accession(s) | NM_004379.4, NM_134442.4, XM_011510645.1, XM_011510647.2 |
| UniProt ID(s) | P16220 |
| UniGene ID(s) | Hs.516646 |
| HGNC ID(s) | HGNC:2345 |
| COSMIC ID Link(s) | CREB1 |
| KEGG Gene ID(s) | hsa:1385 |
| PharmGKB ID(s) | PA26864 |
| General Description of Recombinant Human CREB1 Protein. | |
| Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response elent (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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