PDF DatasheetHuman CSNK1A1 / CKI-alpha / CK1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CSNK1A1 / CKI-alpha / CK1 based upon sequence from Human
Host: QP5879 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CSNK1A1 / CKI-alpha / CK1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5879.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Phe337
Amino Acid Sequence: ASSSGSKAEF IVGGKYKLVR KIGSGSFGDI YLAINITNGE EVAVKLESQK ARHPQLLYES KLYKILQGGV GIPHIRWYGQ EKDYNVLVMD LLGPSLEDLF NFCSRRFTMK TVLMLADQMI SRIEYVHTKN FIHRDIKPDN FLMGIGRHCN KLFLIDFGLA KKYRDNRTRQ HIPYREDKNL TGTARYASIN AHLGIEQSRR DDMESLGYVL MYFNRTSLPW QGLKAATKKQ KYEKISEKKM STPVEVLCKG FPAEFAMYLN YCRGLRFEEA PDYMYLRQLF RILFRTLNHQ YDYTFDWTML KQKAAQQAAS SSGQGQQAQT PTGKQTDKTK SNMKGF
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human CSNK1A1 / CKI-alpha / CK1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CSNK1A1 / CKI-alpha / CK1 Protein General Information | |
|---|---|
| Alternate Names | |
| CSNK1A1, CKI-alpha, CK1, HEL-S-77p, HLCDGP1, CK1, PRO2975, CKIa, CK1a | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CSNK1A1 |
| Entrez Gene ID | 1452 |
| Ensemble Gene ID | ENSG00000113712 |
| RefSeq Protein Accession(s) | NP_001020276.1 |
| RefSeq mRNA Accession(s) | NM_001025105.2, NM_001271741.1, NM_001271742.1, NM_001892.5 |
| UniProt ID(s) | P48729 |
| UniGene ID(s) | Hs.529862 |
| HGNC ID(s) | HGNC:2451 |
| COSMIC ID Link(s) | CSNK1A1 |
| KEGG Gene ID(s) | hsa:1452 |
| PharmGKB ID(s) | PA26951 |
| General Description of Recombinant Human CSNK1A1 / CKI-alpha / CK1 Protein. | |
| Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at ‘Ser-45’. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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