PDF DatasheetHuman Casein kinase I isoform epsilon Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Casein kinase I isoform epsilon based upon sequence from Human
Host: QP5880 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Casein kinase I isoform epsilon, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5880.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Lys416
Amino Acid Sequence: MELRVGNKYR LGRKIGSGSF GDIYLGANIA SGEEVAIKLE CVKTKHPQLH IESKFYKMMQ GGVGIPSIKW CGAEGDYNVM VMELLGPSLE DLFNFCSRKF SLKTVLLLAD QMISRIEYIH SKNFIHRDVK PDNFLMGLGK KGNLVYIIDF GLAKKYRDAR THQHIPYREN KNLTGTARYA SINTHLGIEQ SRRDDLESLG YVLMYFNLGS LPWQGLKAAT KRQKYERISE KKMSTPIEVL CKGYPSEFST YLNFCRSLRF DDKPDYSYLR QLFRNLFHRQ GFSYDYVFDW NMLKFGAARN PEDVDRERRE HEREERMGQL RGSATRALPP GPPTGATANR LRSAAEPVAS TPASRIQPAG NTSPRAISRV DRERKVSMRL HRGAPANVSS SDLTGRQEVS RIPASQTSVP FDHLGK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Casein kinase I isoform epsilon Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Casein kinase I isoform epsilon Protein General Information | |
|---|---|
| Alternate Names | |
| CKIepsilon, HCKIE | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CSNK1E |
| Entrez Gene ID | 102800317 |
| Ensemble Gene ID | ENSG00000213923 |
| RefSeq Protein Accession(s) | NP_001276841.1 |
| RefSeq mRNA Accession(s) | NM_001289912.1, NM_001894.4, NM_152221.2 |
| UniProt ID(s) | P49674 |
| UniGene ID(s) | Hs.474833 |
| HGNC ID(s) | HGNC:2453 |
| COSMIC ID Link(s) | CSNK1E |
| KEGG Gene ID(s) | hsa:102800317 |
| PharmGKB ID(s) | PA26953 |
| General Description of Recombinant Human Casein kinase I isoform epsilon Protein. | |
| Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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