PDF DatasheetHuman Cytochrome b-245 heavy chain Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Cytochrome b-245 heavy chain based upon sequence from Human
Host: QP5899 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Cytochrome b-245 heavy chain, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5899.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Glu283 – Phe570
Amino Acid Sequence: ERLVRFWRSQ QKVVITKVVT HPFKTIELQM KKKGFKMEVG QYIFVKCPKV SKLEWHPFTL TSAPEEDFFS IHIRIVGDWT EGLFNACGCD KQEFQDAWKL PKIAVDGPFG TASEDVFSYE VVMLVGAGIG VTPFASILKS VWYKYCNNAT NLKLKKIYFY WLCRDTHAFE WFADLLQLLE SQMQERNNAG FLSYNIYLTG WDESQANHFA VHHDEEKDVI TGLKQKTLYG RPNWDNEFKT IASQHPNTRI GVFLCGPEAL AETLSKQSIS NSESGPRGVH FIFNKENF
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Cytochrome b-245 heavy chain Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Cytochrome b-245 heavy chain Protein General Information | |
|---|---|
| Alternate Names | |
| CGD, IMD34, GP91-PHOX, NOX2, GP91PHOX, AMCBX2, GP91-1, p91-PHOX | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CYBB |
| Entrez Gene ID | 1536 |
| Ensemble Gene ID | ENSG00000165168 |
| RefSeq Protein Accession(s) | NP_000388.2 |
| RefSeq mRNA Accession(s) | NM_000397.3 |
| UniProt ID(s) | P04839 |
| UniGene ID(s) | Hs.292356 |
| HGNC ID(s) | HGNC:2578 |
| COSMIC ID Link(s) | CYBB |
| KEGG Gene ID(s) | hsa:1536 |
| PharmGKB ID(s) | PA27076 |
| General Description of Recombinant Human Cytochrome b-245 heavy chain Protein. | |
| Critical component of the mbrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from Cytoplasmic domain NADPH across the plasma mbrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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