PDF DatasheetHuman DCX Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant DCX based upon sequence from Human
Host: QP5920 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) DCX, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5920.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Met441
Amino Acid Sequence: MKTLPLHSHC TEMQRLLPKL EMLTLGSSFC SLQGEFCQAM DSFTTVSHVG MCEETDASFN VFSPKFQFDR SHCQSLRFHQ NMELDFGHFD ERDKTSRNMR GSRMNGLPSP THSAHCSFYR TRTLQALSNE KKAKKVRFYR NGDRYFKGIV YAVSSDRFRS FDALLADLTR SLSDNINLPQ GVRYIYTIDG SRKIGSMDEL EEGESYVCSS DNFFKKVEYT KNVNPNWSVN VKTSANMKAP QSLASSNSAQ ARENKDFVRP KLVTIIRSGV KPRKAVRVLL NKKTAHSFEQ VLTDITEAIK LETGVVKKLY TLDGKQVTCL HDFFGDDDVF IACGPEKFRY AQDDFSLDEN ECRVMKGNPS ATAGPKASPT PQKTSAKSPG PMRRSKSPAD SANGTSSSQL STPKSKQSPI STPTSPGSLR KHKDLYLPLS LDDSDSLGDS M
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human DCX Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human DCX Protein General Information | |
|---|---|
| Alternate Names | |
| DCX, SCLH, LISX, DC, XLIS, DBCN | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DCX |
| Entrez Gene ID | 1641 |
| Ensemble Gene ID | ENSG00000077279 |
| RefSeq Protein Accession(s) | NP_000546.2 |
| RefSeq mRNA Accession(s) | NM_000555.3, NM_178151.2, NM_178152.2, NM_178153.2 |
| UniProt ID(s) | O43602 |
| UniGene ID(s) | Hs.34780 |
| HGNC ID(s) | HGNC:2714 |
| COSMIC ID Link(s) | DCX |
| KEGG Gene ID(s) | hsa:1641 |
| PharmGKB ID(s) | PA27184 |
| General Description of Recombinant Human DCX Protein. | |
| Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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