PDF DatasheetHuman Death effector domain-containing protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Death effector domain-containing protein based upon sequence from Human
Host: QP5923 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Death effector domain-containing protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5923.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Pro318
Amino Acid Sequence: MAGLKRRASQ VWPEEHGEQE HGLYSLHRMF DIVGTHLTHR DVRVLSFLFV DVIDDHERGL IRNGRDFLLA LERQGRCDES NFRQVLQLLR IITRHDLLPY VTLKRRRAVC PDLVDKYLEE TSIRYVTPRA LSDPEPRPPQ PSKTVPPHYP VVCCPTSGPQ MCSKRPARGR ATLGSQRKRR KSVTPDPKEK QTCDIRLRVR AEYCQHETAL QGNVFSNKQD PLERQFERFN QANTILKSRD LGSIICDIKF SELTYLDAFW RDYINGSLLE ALKGVFITDS LKQAVGHEAI KLLVNVDEED YELGRQKLLR NLMLQALP
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Death effector domain-containing protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Death effector domain-containing protein Protein General Information | |
|---|---|
| Alternate Names | |
| DEFT, CASP8IP1, KE05, DEDD1, FLDED1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DEDD |
| Entrez Gene ID | 9191 |
| Ensemble Gene ID | ENSG00000158796 |
| RefSeq Protein Accession(s) | NP_001034800.1 |
| RefSeq mRNA Accession(s) | NM_001039711.1, NM_001039712.1, NM_032998.2, XM_017002802.1 |
| UniProt ID(s) | O75618 |
| UniGene ID(s) | Hs.744092 |
| HGNC ID(s) | HGNC:2755 |
| COSMIC ID Link(s) | DEDD |
| KEGG Gene ID(s) | hsa:9191 |
| PharmGKB ID(s) | PA27236 |
| General Description of Recombinant Human Death effector domain-containing protein Protein. | |
| A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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