PDF DatasheetHuman Density-regulated protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Density-regulated protein based upon sequence from Human
Host: QP5928 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Density-regulated protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5928.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Lys198
Amino Acid Sequence: AADISESSGA DCKGDPRNSA KLDADYPLRV LYCGVCSLPT EYCEYMPDVA KCRQWLEKNF PNEFAKLTVE NSPKQEAGIS EGQGTAGEEE EKKKQKRGGR GQIKQKKKTV PQKVTIAKIP RAKKKYVTRV CGLATFEIDL KEAQRFFAQK FSCGASVTGE DEIIIQGDFT DDIIDVIQEK WPEVDDDSIE DLGEVKK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Density-regulated protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Density-regulated protein Protein General Information | |
|---|---|
| Alternate Names | |
| SMAP-3, DRP1, DRP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DENR |
| Entrez Gene ID | 8562 |
| Ensemble Gene ID | ENSG00000139726 |
| RefSeq Protein Accession(s) | NP_003668.2 |
| RefSeq mRNA Accession(s) | NM_003677.4 |
| UniProt ID(s) | O43583 |
| UniGene ID(s) | Hs.22393 |
| HGNC ID(s) | HGNC:2769 |
| COSMIC ID Link(s) | DENR |
| KEGG Gene ID(s) | hsa:8562 |
| PharmGKB ID(s) | PA27252 |
| General Description of Recombinant Human Density-regulated protein Protein. | |
| May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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