PDF DatasheetHuman DNTTIP1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant DNTTIP1 based upon sequence from Human
Host: QP5942 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) DNTTIP1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5942.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Thr329
Amino Acid Sequence: MGATGDAEQP RGPSGAERGG LELGDAGAAG QLVLTNPWNI MIKHRQVQRR GRRSQMTTSF TDPAISMDLL RAVLQPSINE EIQTVFNKYM KFFQKAALNV RDNVGEEVDA EQLIQEACRS CLEQAKLLFS DGEKVIPRLT HELPGIKRGR QAEEECAHRG SPLPKKRKGR PPGHILSSDR AAAGMVWKPK SCEPIRREGP KWDPARLNES TTFVLGSRAN KALGMGGTRG RIYIKHPHLF KYAADPQDKH WLAEQHHMRA TGGKMAYLLI EEDIRDLAAS DDYRGCLDLK LEELKSFVLP SWMVEKMRKY METLRTENEH RAVEAPPQT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human DNTTIP1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human DNTTIP1 Protein General Information | |
|---|---|
| Alternate Names | |
| dJ447F3.4, Tdif1, C20orf167, Deoxynucleotidyltransferase terminal-interacting protein | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DNTTIP1 |
| Entrez Gene ID | 116092 |
| Ensemble Gene ID | ENSG00000101457 |
| RefSeq Protein Accession(s) | NP_443183.1 |
| RefSeq mRNA Accession(s) | NM_052951.2 |
| UniProt ID(s) | Q9H147 |
| UniGene ID(s) | Hs.472852 |
| HGNC ID(s) | HGNC:16160 |
| COSMIC ID Link(s) | DNTTIP1 |
| KEGG Gene ID(s) | hsa:116092 |
| PharmGKB ID(s) | PA25709 |
| General Description of Recombinant Human DNTTIP1 Protein. | |
| Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro) . Also acts as a transcriptional regulator, binding to the consensus sequence 5′-GNTGCATG-3′ following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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