PDF DatasheetHuman Docking protein 5 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Docking protein 5 based upon sequence from Human
Isoform: Isoform 2
Host: QP5943 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Docking protein 5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5943.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details). of Isoform 2
Expression Region: Met1 – His198
Amino Acid Sequence: MECVGTRIND ISLGEPDLLA TGVEREQSER FNVYLMPSPN LDVHGECALQ ITYEYICLWD VQNPRVKLIS WPLSALRRYG RDTTWFTFEA GRMCETGEGL FIFQTRDGEA IYQKVHSAAL AIAEQHERLL QSVKNSMLQM KMSERAASLS TMVPLPRSAY WQHITRQHST GQLYRLQDVS SPLKLHRTET FPAYRSEH
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Docking protein 5 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Docking protein 5 Protein General Information | |
|---|---|
| Alternate Names | |
| C20orf180, IRS6, IRS-6 | |
| Molecular Weight | |
| Isoform 2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DOK5 |
| Entrez Gene ID | 55816 |
| Ensemble Gene ID | ENSG00000101134 |
| RefSeq Protein Accession(s) | NP_060901.2 |
| RefSeq mRNA Accession(s) | NM_018431.4, NM_177959.2, XM_011528904.1 |
| UniProt ID(s) | Q9P104 |
| UniGene ID(s) | Hs.473133 |
| HGNC ID(s) | HGNC:16173 |
| COSMIC ID Link(s) | DOK5 |
| KEGG Gene ID(s) | hsa:55816 |
| PharmGKB ID(s) | PA25724 |
| General Description of Recombinant Human Docking protein 5 Protein. | |
| DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assbly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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