PDF DatasheetHuman Protein Dr1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Protein Dr1 based upon sequence from Human
Host: QP5946 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Protein Dr1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5946.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala1 – Ile176
Amino Acid Sequence: ASSSGNDDDL TIPRAAINKM IKETLPNVRV ANDARELVVN CCTEFIHLIS SEANEICNKS EKKTISPEHV IQALESLGFG SYISEVKEVL QECKTVALKR RKASSRLENL GIPEEELLRQ QQELFAKARQ QQAELAQQEW LQMQQAAQQA QLAAASASAS NQAGSSQDEE DDDDI
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Protein Dr1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Protein Dr1 Protein General Information | |
|---|---|
| Alternate Names | |
| NC2, NC2-BETA, NC2B | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DR1 |
| Entrez Gene ID | 1810 |
| Ensemble Gene ID | ENSG00000117505 |
| RefSeq Protein Accession(s) | NP_001929.1 |
| RefSeq mRNA Accession(s) | NM_001938.2 |
| UniProt ID(s) | Q01658 |
| UniGene ID(s) | Hs.348418 |
| HGNC ID(s) | HGNC:3017 |
| COSMIC ID Link(s) | DR1 |
| KEGG Gene ID(s) | hsa:1810 |
| PharmGKB ID(s) | PA27475 |
| General Description of Recombinant Human Protein Dr1 Protein. | |
| The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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