PDF DatasheetMouse Ephrin B3 / EFNB3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Ephrin B3 / EFNB3 based upon sequence from Mouse
Host: QP5967 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Ephrin B3 / EFNB3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5967.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Leu28 – Ala227
Amino Acid Sequence: LSLEPVYWNS ANKRFQAEGG YVLYPQIGDR LDLLCPRARP PGPHSSPSYE FYKLYLVEGA QGRRCEAPPA PNLLLTCDRP DLDLRFTIKF QEYSPNLWGH EFRSHHDYYI IATSDGTREG LESLQGGVCL TRGMKVLLRV GQSPRGGAVP RKPVSEMPME RDRGAAHSAE PGRDTIPGDP SSNATSRGAE GPLPPPSMPA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Ephrin B3 / EFNB3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Ephrin B3 / EFNB3 Protein General Information | |
|---|---|
| Alternate Names | |
| Ephrin B3, EFNB3, EFL-6, Epl8, Elk-L3, ELF-3, LERK-8, NLERK-2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Efnb3 |
| Entrez Gene ID | 13643 |
| Ensemble Gene ID | ENSMUSG00000003934 |
| RefSeq Protein Accession(s) | NP_031937.1 |
| RefSeq mRNA Accession(s) | NM_007911.5 |
| UniProt ID(s) | O35393 |
| UniGene ID(s) | Mm.249637 |
| COSMIC ID Link(s) | Efnb3 |
| KEGG Gene ID(s) | mmu:13643 |
| General Description of Recombinant Mouse Ephrin B3 / EFNB3 Protein. | |
| Cell surface transmbrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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