PDF DatasheetHuman EIF3G Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant EIF3G based upon sequence from Human
Host: QP5972 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) EIF3G, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5972.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Pro2 – Asn320
Amino Acid Sequence: PTGDFDSKPS WADQVEEEGE DDKCVTSELL KGIPLATGDT SPEPELLPGA PLPPPKEVIN GNIKTVTEYK IDEDGKKFKI VRTFRIETRK ASKAVARRKN WKKFGNSEFD PPGPNVATTT VSDDVSMTFI TSKEDLNCQE EEDPMNKLKG QKIVSCRICK GDHWTTRCPY KDTLGPMQKE LAEQLGLSTG EKEKLPGELE PVQATQNKTG KYVPPSLRDG ASRRGESMQP NRRADDNATI RVTNLSEDTR ETDLQELFRP FGSISRIYLA KDKTTGQSKG FAFISFHRRE DAARAIAGVS GFGYDHLILN VEWAKPSTN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human EIF3G Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human EIF3G Protein General Information | |
|---|---|
| Alternate Names | |
| EIF3-P42, eIF3-delta, EIF3S4, eIF3-p44, Eukaryotic translation initiation factor 3 subunit | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | EIF3G |
| Entrez Gene ID | 8666 |
| Ensemble Gene ID | ENSG00000130811 |
| RefSeq Protein Accession(s) | NP_003746.2 |
| RefSeq mRNA Accession(s) | NM_003755.4 |
| UniProt ID(s) | O75821 |
| UniGene ID(s) | Hs.529059 |
| HGNC ID(s) | HGNC:3274 |
| COSMIC ID Link(s) | EIF3G |
| KEGG Gene ID(s) | hsa:8666 |
| PharmGKB ID(s) | PA162384827 |
| General Description of Recombinant Human EIF3G Protein. | |
| Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassbly and recycling of post-termination ribosomal complexes and subsequently prevents prature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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