PDF DatasheetHuman Bifunctional epoxide hydrolase 2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Bifunctional epoxide hydrolase 2 based upon sequence from Human
Host: QP5986 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Bifunctional epoxide hydrolase 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5986.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Met555
Amino Acid Sequence: MTLRAAVFDL DGVLALPAVF GVLGRTEEAL ALPRGLLNDA FQKGGPEGAT TRLMKGEITL SQWIPLMEEN CRKCSETAKV CLPKNFSIKE IFDKAISARK INRPMLQAAL MLRKKGFTTA ILTNTWLDDR AERDGLAQLM CELKMHFDFL IESCQVGMVK PEPQIYKFLL DTLKASPSEV VFLDDIGANL KPARDLGMVT ILVQDTDTAL KELEKVTGIQ LLNTPAPLPT SCNPSDMSHG YVTVKPRVRL HFVELGSGPA VCLCHGFPES WYSWRYQIPA LAQAGYRVLA MDMKGYGESS APPEIEEYCM EVLCKEMVTF LDKLGLSQAV FIGHDWGGML VWYMALFYPE RVRAVASLNT PFIPANPNMS PLESIKANPV FDYQLYFQEP GVAEAELEQN LSRTFKSLFR ASDESVLSMH KVCEAGGLFV NSPEEPSLSR MVTEEEIQFY VQQFKKSGFR GPLNWYRNME RNWKWACKSL GRKILIPALM VTAEKDFVLV PQMSQHMEDW IPHLKRGHIE DCGHWTQMDK PTEVNQILIK WLDSDARNPP VVSKM
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Bifunctional epoxide hydrolase 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Bifunctional epoxide hydrolase 2 Protein General Information | |
|---|---|
| Alternate Names | |
| SEH, CEH | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | EPHX2 |
| Entrez Gene ID | 2053 |
| Ensemble Gene ID | ENSG00000120915 |
| RefSeq Protein Accession(s) | NP_001243411.1 |
| RefSeq mRNA Accession(s) | NM_001256482.1, NM_001256483.1, NM_001256484.1, NM_001979.5 |
| UniProt ID(s) | P34913 |
| UniGene ID(s) | Hs.212088 |
| HGNC ID(s) | HGNC:3402 |
| KEGG Gene ID(s) | hsa:2053 |
| PharmGKB ID(s) | PA27830 |
| General Description of Recombinant Human Bifunctional epoxide hydrolase 2 Protein. | |
| Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid, 12-phosphonooxy-octadec-9E-enoic acid, and p-nitrophenyl phospate. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.