PDF DatasheetHuman DNA repair protein complementing XP-G cells Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant DNA repair protein complementing XP-G cells based upon sequence from Human
Host: QP5994 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) DNA repair protein complementing XP-G cells, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5994.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser947 – Thr1186
Amino Acid Sequence: SFLWGKPDLD KIREFCQRYF GWNRTKTDES LFPVLKQLDA QQTQLRIDSF FRLAQQEKED AKRIKSQRLN RAVTCMLRKE KEAAASEIEA VSVAMEKEFE LLDKAKGKTQ KRGITNTLEE SSSLKRKRLS DSKGKNTCGG FLGETCLSES SDGSSSEDAE SSSLMNVQRR TAAKEPKTSA SDSQNSVKEA PVKNGGATTS SSSDSDDDGG KEKMVLVTAR SVFGKKRRKL RRARGRKRKT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human DNA repair protein complementing XP-G cells Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human DNA repair protein complementing XP-G cells Protein General Information | |
|---|---|
| Alternate Names | |
| UVDR, XPGC, XPG, ERCM2, COFS3, ERCC5-201 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ERCC5 |
| Entrez Gene ID | 2073 |
| Ensemble Gene ID | ENSG00000134899 |
| RefSeq Protein Accession(s) | NP_000114.2 |
| RefSeq mRNA Accession(s) | NM_000123.3 |
| UniProt ID(s) | P28715 |
| UniGene ID(s) | Hs.258429 |
| HGNC ID(s) | HGNC:3437 |
| COSMIC ID Link(s) | ERCC5 |
| KEGG Gene ID(s) | hsa:2073 |
| PharmGKB ID(s) | PA27851 |
| General Description of Recombinant Human DNA repair protein complementing XP-G cells Protein. | |
| Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3’incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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