PDF DatasheetHuman Steroid hormone receptor ERR1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Steroid hormone receptor ERR1 based upon sequence from Human
Host: QP6001 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Steroid hormone receptor ERR1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6001.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: MSSQVVGIEP LYIKAEPASP DSPKGSSETE TEPPVALAPG PAPTRCLPGH KEEEDGEGAG PGEQGGGKLV LSSLPKRLCL VCGDVASGYH YGVASCEACK AFFKRTIQGS IEYSCPASNE CEITKRRRKA CQACRFTKCL RVGMLKEGVR LDRVRGGRQK YKRRPEVDPL PFPGPFPAGP LAVAGGPRKT AAPVNALVSH LLVVEPEKLY AMPDPAGPDG HLPAVATLCD LFDREIVVTI SWAKSIPGFS SLSLSDQMSV LQSVWMEVLV LGVAQRSLPL QDELAFAEDL VLDEEGARAA GLGELGAALL QLVRRLQALR LEREEYVLLK ALALANSDSV HIEDAEAVEQ LREALHEALL EYEAGRAGPG GGAERRRAGR LLLTLPLLRQ TAGKVLAHFY GVKLEGKVPM HKLFLEMLEA MMD
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Steroid hormone receptor ERR1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Steroid hormone receptor ERR1 Protein General Information | |
|---|---|
| Alternate Names | |
| ERR1, ESRL1, NR3B1, ERRa, ERRalpha | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ESRRA |
| Entrez Gene ID | 2101 |
| Ensemble Gene ID | ENSG00000173153 |
| RefSeq Protein Accession(s) | NP_001269379.1 |
| RefSeq mRNA Accession(s) | NM_001282450.1, NM_001282451.1, NM_004451.4 |
| UniProt ID(s) | P11474 |
| UniGene ID(s) | Hs.110849 |
| HGNC ID(s) | HGNC:3471 |
| COSMIC ID Link(s) | ESRRA |
| KEGG Gene ID(s) | hsa:2101 |
| PharmGKB ID(s) | PA27887 |
| General Description of Recombinant Human Steroid hormone receptor ERR1 Protein. | |
| Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5′-TNAAGGTCA-3′. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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