PDF DatasheetHuman Coagulation Factor VII / FVII / F7 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Coagulation Factor VII / FVII / F7 based upon sequence from Human
Host: QP6012 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Coagulation Factor VII / FVII / F7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6012.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ala61 – Arg212
Amino Acid Sequence: ANAFLEELRP GSLERECKEE QCSFEEAREI FKDAERTKLF WISYSDGDQC ASSPCQNGGS CKDQLQSYIC FCLPAFEGRN CETHKDDQLI CVNENGGCEQ YCSDHTGTKR SCRCHEGYSL LADGVSCTPT VEYPCGKIPI LEKRNASKPQ GR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Coagulation Factor VII / FVII / F7 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Coagulation Factor VII / FVII / F7 Protein General Information | |
|---|---|
| Alternate Names | |
| Coagulation Factor VII, FVII, F7, Cf7, AI132620, FVII | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | F7 |
| Entrez Gene ID | 2155 |
| Ensemble Gene ID | ENSG00000057593 |
| RefSeq Protein Accession(s) | NP_000122.1 |
| RefSeq mRNA Accession(s) | NM_000131.4, NM_019616.3 |
| UniProt ID(s) | P08709 |
| UniGene ID(s) | Hs.36989 |
| HGNC ID(s) | HGNC:3544 |
| COSMIC ID Link(s) | F7 |
| KEGG Gene ID(s) | hsa:2155 |
| PharmGKB ID(s) | PA160 |
| General Description of Recombinant Human Coagulation Factor VII / FVII / F7 Protein. | |
| Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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