PDF DatasheetHuman Fatty acid desaturase 2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Fatty acid desaturase 2 based upon sequence from Human
Host: QP6016 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Fatty acid desaturase 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6016.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Val131
Amino Acid Sequence: MGKGGNQGEG AAEREVSVPT FSWEEIQKHN LRTDRWLVID RKVYNITKWS IQHPGGQRVI GHYAGEDATD AFRAFHPDLE FVGKFLKPLL IGELAPEEPS QDHGKNSKIT EDFRALRKTA EDMNLFKTNH V
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Fatty acid desaturase 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Fatty acid desaturase 2 Protein General Information | |
|---|---|
| Alternate Names | |
| D6D, SLL0262, TU13, DES6, FADSD6, LLCDL2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FADS2 |
| Entrez Gene ID | 9415 |
| Ensemble Gene ID | ENSG00000134824 |
| RefSeq Protein Accession(s) | NP_001268430.1 |
| RefSeq mRNA Accession(s) | NM_001281501.1, NM_001281502.1, NM_004265.3 |
| UniProt ID(s) | O95864 |
| UniGene ID(s) | Hs.502745 |
| HGNC ID(s) | HGNC:3575 |
| COSMIC ID Link(s) | FADS2 |
| KEGG Gene ID(s) | hsa:9415 |
| PharmGKB ID(s) | PA27974 |
| General Description of Recombinant Human Fatty acid desaturase 2 Protein. | |
| Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleic acid (GLA) (18:3n-6) and stearidonic acid (18:4n-3) respectively and other desaturation steps. Highly unsaturated fatty acids (HUFA) play pivotal roles in many biological functions. It catalizes as well the introduction of a cis double bond in palmitate to produce the mono-unsaturated fatty acid sapienate, the most abundant fatty acid in sebum. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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