PDF DatasheetMouse Fas apoptotic inhibitory molecule 3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Fas apoptotic inhibitory molecule 3 based upon sequence from Mouse
Host: QP6017 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Fas apoptotic inhibitory molecule 3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6017.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Arg18 – Glu2
Amino Acid Sequence: RVLPEVQLNV EWGGSIIIEC PLPQLHVRMY LCRQMAKPGI CSTVVSNTFV KKEYERRVTL TPCLDKKLFL VEMTQLTEND DGIYACGVGM KTDKGKTQKI TLNVHNEYPE PFWEDEWTSE RPRWLHRFLQ HQMPWLHGSE HPSSSGVIAK VTTPAPKTEA PPVHQPSSIT SVTQHPRVYR AFSVSATKSP ALLPATTASK TSTQQAIRPL EASYSHHTRL HEQRTRHHGP HYGREDRGLH IPIPE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Fas apoptotic inhibitory molecule 3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Fas apoptotic inhibitory molecule 3 Protein General Information | |
|---|---|
| Alternate Names | |
| Faim3, Toso, FcmuR, 1810037B05Rik | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Faim3 |
| Entrez Gene ID | 69169 |
| RefSeq Protein Accession(s) | NP_081252.1 |
| RefSeq mRNA Accession(s) | NM_026976.2 |
| UniProt ID(s) | A1KXC4 |
| UniGene ID(s) | Mm.46042 |
| COSMIC ID Link(s) | Faim3 |
| KEGG Gene ID(s) | mmu:69169 |
| General Description of Recombinant Mouse Fas apoptotic inhibitory molecule 3 Protein. | |
| May play a role in the immune syst processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Ses to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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