PDF DatasheetHuman Fanconi anemia group C protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Fanconi anemia group C protein based upon sequence from Human
Host: QP6019 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Fanconi anemia group C protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6019.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Val558
Amino Acid Sequence: MAQDSVDLSC DYQFWMQKLS VWDQASTLET QQDTCLHVAQ FQEFLRKMYE ALKEMDSNTV IERFPTIGQL LAKACWNPFI LAYDESQKIL IWCLCCLINK EPQNSGQSKL NSWIQGVLSH ILSALRFDKE VALFTQGLGY APIDYYPGLL KNMVLSLASE LRENHLNGFN TQRRMAPERV ASLSRVCVPL ITLTDVDPLV EALLICHGRE PQEILQPEFF EAVNEAILLK KISLPMSAVV CLWLRHLPSL EKAMLHLFEK LISSERNCLR RIECFIKDSS LPQAACHPAI FRVVDEMFRC ALLETDGALE IIATIQVFTQ CFVEALEKAS KQLRFALKTY FPYTSPSLAM VLLQDPQDIP RGHWLQTLKH ISELLREAVE DQTHGSCGGP FESWFLFIHF GGWAEMVAEQ LLMSAAEPPT ALLWLLAFYY GPRDGRQQRA QTMVQVKAVL GHLLAMSRSS SLSAQDLQTV AGQGTDTDLR APAQQLIRHL LLNFLLWAPG GHTIAWDVIT LMAHTAEITH EIIGFLDQTL YRWNRLGIES PRSEKLAREL LKELRTQV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Fanconi anemia group C protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Fanconi anemia group C protein Protein General Information | |
|---|---|
| Alternate Names | |
| FACC, FA3, FAC | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FANCC |
| Entrez Gene ID | 2176 |
| Ensemble Gene ID | ENSG00000158169 |
| RefSeq Protein Accession(s) | NP_000127.2 |
| RefSeq mRNA Accession(s) | NM_000136.2, NM_001243743.1, XM_011518365.2 |
| UniProt ID(s) | Q00597 |
| UniGene ID(s) | Hs.494529 |
| HGNC ID(s) | HGNC:3584 |
| COSMIC ID Link(s) | FANCC |
| KEGG Gene ID(s) | hsa:2176 |
| PharmGKB ID(s) | PA27997 |
| General Description of Recombinant Human Fanconi anemia group C protein Protein. | |
| DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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