PDF DatasheetHuman Fas Ligand / FASLG / CD95L Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Fas Ligand / FASLG / CD95L based upon sequence from Human
Host: QP6021 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Fas Ligand / FASLG / CD95L, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6021.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Gln130 – Leu281
Amino Acid Sequence: QIGHPSPPPE KKELRKVAHL TGKSNSRSMP LEWEDTYGIV LLSGVKYKKG GLVINETGLY FVYSKVYFRG QSCNNLPLSH KVYMRNSKYP QDLVMMEGKM MSYCTTGQMW ARSSYLGAVF NLTSADHLYV NVSELSLVNF EESQTFFGLY KL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Fas Ligand / FASLG / CD95L Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Fas Ligand / FASLG / CD95L Protein (130-281aa) General Information | |
|---|---|
| Alternate Names | |
| Fas Ligand, FASLG, CD95L, TNFSF6, APT1LG1, TNLG1A, CD95-L, ALPS1B, FASL, CD95L, APTL, CD178 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FASLG |
| Entrez Gene ID | 356 |
| Ensemble Gene ID | ENSG00000117560 |
| RefSeq Protein Accession(s) | NP_000630.1 |
| RefSeq mRNA Accession(s) | NM_000639.2, NM_001302746.1 |
| UniProt ID(s) | P48023 |
| UniGene ID(s) | Hs.2007 |
| HGNC ID(s) | HGNC:11936 |
| COSMIC ID Link(s) | FASLG |
| KEGG Gene ID(s) | hsa:356 |
| PharmGKB ID(s) | PA56 |
| General Description of Recombinant Human Fas Ligand / FASLG / CD95L Protein (130-281aa). | |
| Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.