PDF DatasheetHuman FDXR, mitochondrial Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant FDXR, mitochondrial based upon sequence from Human
Isoform: Isoform 6
Host: QP6033 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) FDXR, mitochondrial, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6033.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 6
Expression Region: Ser33 – His451
Amino Acid Sequence: STQEKTPQIC VVGSGPAGFY TAQHLLKQHP QAHVDIYEKQ PVPFGLVRFG VAPDHPEVKS YGAEDHRALE IPGEELPGVC SARAFVGWYN GLPENQELEP DLSCDTAVIL GQGNVALDVA RILLTPPEHL ERTDITKAAL GVLRQSRVKT VWLVGRRGPL QVAFTIKELR EMIQLPGARP ILDPVDFLGL QDKIKEVPRP RKRLTELLLR TATEKPGPAE AARQASASRA WGLRFFRSPQ QVLPSPDGRR AAGVRLAVTR LEGVDEATRA VPTGDMEDLP CGLVLSSIGY KSRPVDPSVP FDSKLGVIPN VEGRVMDVPG LYCSGWVKRG PTGVIATTMT DSFLTGQMLL QDLKAGLLPS GPRPGYAAIQ ALLSSRGVRP VSFSDWEKLD AEEVARGQGT GKPREKLVDP QEMLRLLGH
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human FDXR, mitochondrial Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human FDXR, mitochondrial Protein General Information | |
|---|---|
| Alternate Names | |
| ADXR, NADPH:adrenodoxin oxidoreductase, mitochondri | |
| Molecular Weight | |
| Isoform 6 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FDXR |
| Entrez Gene ID | 2232 |
| Ensemble Gene ID | ENSG00000161513 |
| RefSeq Protein Accession(s) | NP_001244941.2 |
| RefSeq mRNA Accession(s) | NM_001258012.3, NM_001258013.3, NM_001258014.3, NM_001258015.2, NM_001258016.3, NM_004110.5, NM_024417.4 |
| UniProt ID(s) | P22570 |
| UniGene ID(s) | Hs.69745 |
| HGNC ID(s) | HGNC:3642 |
| COSMIC ID Link(s) | FDXR |
| KEGG Gene ID(s) | hsa:2232 |
| PharmGKB ID(s) | PA28086 |
| General Description of Recombinant Human FDXR, mitochondrial Protein. | |
| Serves as the first electron transfer protein in all the mitochondrial P450 systs. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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