PDF DatasheetHuman Sperm-egg fusion protein Juno Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Sperm-egg fusion protein Juno based upon sequence from Human
Host: QP6052 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Sperm-egg fusion protein Juno, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6052.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly20 – Ser250
Amino Acid Sequence: GDELLNICMN AKHHKRVPSP EDKLYEECIP WKDNACCTLT TSWEAHLDVS PLYNFSLFHC GLLMPGCRKH FIQAICFYEC SPNLGPWIQP VGSLGWEVAP SGQGERVVNV PLCQEDCEEW WEDCRMSYTC KSNWRGGWDW SQGKNRCPKG AQCLPFSHYF PTPADLCEKT WSNSFKASPE RRNSGRCLQK WFEPAQGNPN VAVARLFASS APSWELSYTI MVCSLFLPFL S
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Sperm-egg fusion protein Juno Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Sperm-egg fusion protein Juno Protein General Information | |
|---|---|
| Alternate Names | |
| FOLR4, Folbp3, JUNO | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IZUMO1R |
| Entrez Gene ID | 390243 |
| Ensemble Gene ID | ENSG00000183560 |
| RefSeq Protein Accession(s) | NP_001186135.1 |
| RefSeq mRNA Accession(s) | NM_001199206.1 |
| UniProt ID(s) | A6ND01 |
| UniGene ID(s) | Hs.553758 |
| HGNC ID(s) | HGNC:32565 |
| KEGG Gene ID(s) | hsa:390243 |
| General Description of Recombinant Human Sperm-egg fusion protein Juno Protein. | |
| Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane ‘fusogen’. Does not bind folate (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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