PDF DatasheetMouse Frataxin, mitochondrial Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Frataxin, mitochondrial based upon sequence from Mouse
Host: QP6059 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Frataxin, mitochondrial, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6059.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Leu78 – Thr207
Amino Acid Sequence: LGTLDNPSSL DETAYERLAE ETLDSLAEFF EDLADKPYTL EDYDVSFGDG VLTIKLGGDL GTYVINKQTP NKQIWLSSPS SGPKRYDWTG KNWVYSHDGV SLHELLAREL TKALNTKLDL SSLAYSGKGT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Frataxin, mitochondrial Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Frataxin, mitochondrial Protein General Information | |
|---|---|
| Alternate Names | |
| FARR, X25, FA, Frda | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Fxn |
| Entrez Gene ID | 14297 |
| Ensemble Gene ID | ENSMUSG00000059363 |
| RefSeq Protein Accession(s) | NP_032070.1 |
| RefSeq mRNA Accession(s) | NM_008044.2 |
| UniProt ID(s) | O35943 |
| UniGene ID(s) | Mm.7319 |
| COSMIC ID Link(s) | Fxn |
| KEGG Gene ID(s) | mmu:14297 |
| General Description of Recombinant Mouse Frataxin, mitochondrial Protein. | |
| Promotes the biosynthesis of he and assbly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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