PDF DatasheetHuman GADD45A / DDIT-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant GADD45A / DDIT-1 based upon sequence from Human
Host: QP6063 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) GADD45A / DDIT-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6063.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Arg165
Amino Acid Sequence: MTLEEFSAGE QKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQA FCCENDINIL RVSNPGRLAE LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVI NLPER
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human GADD45A / DDIT-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human GADD45A / DDIT-1 Protein General Information | |
|---|---|
| Alternate Names | |
| GADD45A, DDIT-1, DDIT1, GADD45 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GADD45A |
| Entrez Gene ID | 1647 |
| Ensemble Gene ID | ENSG00000116717 |
| RefSeq Protein Accession(s) | NP_001186670.1 |
| RefSeq mRNA Accession(s) | NM_001199741.1, NM_001199742.1, NM_001924.3 |
| UniProt ID(s) | P24522 |
| UniGene ID(s) | Hs.80409 |
| HGNC ID(s) | HGNC:4095 |
| COSMIC ID Link(s) | GADD45A |
| KEGG Gene ID(s) | hsa:1647 |
| PharmGKB ID(s) | PA28510 |
| General Description of Recombinant Human GADD45A / DDIT-1 Protein. | |
| In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity . Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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